Starvation marrow – gelatinous transformation of bone marrow

Starvation marrow – gelatinous transformation of bone marrow

Gelatinous bone marrow transformation (GMT), also known as starvation marrow, represents a rare pathological entity of unclear etiology, in which bone marrow histopathology demonstrates hypoplasia, fat atrophy, and gelatinous infiltration. The finding of gelatinous marrow transformation lacks disease specificity; rather, it is an indicator of severe illness and a marker of poor nutritional stat...

Gelatinous transformation of bone marrow

Clinical profile in gelatinous bone marrow transformation.

OBJECTIVE To study the clinical spectrum associated with gelatinous bone marrow transformation (GMT). METHODS All subjects whose bone marrow aspiration showed pink purple material on Leishman stain underwent a detail history, clinical examination and investigation (biochemical/microbiological/radiological). Additionally, in each subject the smear was stained with special stains of Periodic Ac...

Gelatinous Transformation of the Bone Marrow: A Rare Presentation

Gelatinous bone marrow transformation (GMT) is a rare disorder of unknown pathogenesis. It is characterized by fat cell atrophy, focal loss of hematopoietic cells and deposition of extracellular gelatinous substances, which histochemically are mucopolysaccharides and rich in hyaluronic acid. GMT occurs more often in adults males than in females. The spectrum of underlying diseases is heterogene...

Gelatinous transformation of the bone marrow in hepatocellular carcinoma

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 52-year-old woman with a history of hepatocellular carcinoma with bone metastasis (T6, L5-S1) was referred for pancytopenia after undergoing radiation therapy and transarterial chemoembolization. Splenomegaly and compact lipiodol retention in liver segment...